Mouse Allograft Inflammatory Factor 1, AIF1 ELI

Actin-binding protein that enhances membrane ruffling and RAC activation.

Enhances the actin-bundling activity of LCP1.

Binds calcium.

Plays a role in RAC signaling and in phagocytosis.

May play a role in macrophage activation and function.

Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes.

Enhances lymphocyte migration.

Plays a role in vascular inflammation.