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Mouse Caspase 14,CASP14 ELI
Price
3,140.00 ₪
Non-apoptotic caspase which is involved in epidermal differentiation.
Seems to play a role in keratinocyte differentiation and is required for cornification (PubMed:18156206).
Regulates maturation of the epidermis by proteolytically processing filaggrin (PubMed:21654840).
In vitro is equally active on the synthetic caspase substrates WEHD-ACF and IETD-AFC.
Involved in processing of prosaposin in the epidermis (PubMed:24872419).
May be involved in retinal pigment epithelium cell barrier function (By similarity).
{ECO:0000250|UniProtKB:P31944, ECO:0000269|PubMed:11175259, ECO:0000269|PubMed:17515931, ECO:0000269|PubMed:18156206, ECO:0000269|PubMed:21654840, ECO:0000269|PubMed:24872419}.
Quantity
Storage and Stability
2-8ºC
Sensitivity
0.19ng/ml
Detection range
0.38-24ng/ml
Shipping Conditions
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