Mouse Cytochrome B-245 Heavy Chain, CYBB ELI

Critical component of the membrane-bound oxidase of phagocytes that generates superoxide.

It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior.

Also functions as a voltage-gated proton channel that mediates the H+ currents of resting phagocytes.