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Mouse Dickkopf 1,DKK1 ELI

Price

‏3,140.00 ‏₪

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6 (PubMed:18524778).

Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity (PubMed:26206087).

Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning (PubMed:18505822).

{ECO:0000269|PubMed:18505822, ECO:0000269|PubMed:18524778, ECO:0000269|PubMed:26206087}.

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

16.15ng/L

Detection range

30-9000ng/L

Shipping Conditions

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