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Mouse Dickkopf-related Protein 1, DKK1 ELI

Price

‏3,140.00 ‏₪

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6 (PubMed: 18524778).

Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity (PubMed: 26206087).

Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning (PubMed: 18505822).

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

14.12ng/L

Detection range

30-9000ng/L

Shipping Conditions

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