Mouse Follistatin Like Protein 1,FSTL1 ELI

Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation (By similarity).

Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter (PubMed:21826198, PubMed:19595790).

Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner.

Also promotes survival of cardiac myocytes (PubMed:20054002).

Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors (By similarity).

{ECO:0000250|UniProtKB:Q12841, ECO:0000269|PubMed:19595790, ECO:0000269|PubMed:20054002, ECO:0000269|PubMed:21826198}.