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Mouse Interleukin 1 Receptor 2,IL1R2 ELI

Price

‏3,140.00 ‏₪

Non-signaling receptor for IL1A, IL1B and IL1RN.

Reduces IL1B activities.

Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1.

Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B.

IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN.

The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors (By similarity).

{ECO:0000250, ECO:0000269|PubMed:8332913, ECO:0000269|PubMed:9662436}.

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

2.51ng/L

Detection range

5-2000ng/L

Shipping Conditions

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