Mouse Interleukin 4, IL-4 ELI

Participates in at least several B-cell activation processes as well as of other cell types (PubMed: 3083412).

It is a costimulator of DNA-synthesis.

It induces the expression of class II MHC molecules on resting B-cells (PubMed: 3$498.00|$360.00301).

It enhances both secretion and cell surface expression of IgE and IgG1 (PubMed: 3$498.00|$360.00301).

It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.

Positively regulates IL31RA expression in macrophages (PubMed: 25847241).

Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4 (PubMed: 26416964).