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Mouse latent transforming growth factor beta binding protein 1,LTBP1 ELI

Price

‏3,140.00 ‏₪

Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space.

Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta.

Outcompeted by LRRC32/GARP for binding to LAP regulatory chain of TGF-beta.

{ECO:0000250|UniProtKB:Q14766}.

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

0.1ng/ml

Detection range

0.19-12ng/ml

Shipping Conditions

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