Mouse Mesoderm-specific Transcript Homolog Protein, MEST ELI

Mesoderm-specific transcript homolog protein is a protein that in humans is encoded by the MEST gene.

This gene encodes a member of the Alpha/beta hydrolase superfamily and has isoform-specific imprinting.

The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promoter switching.

The encoded protein may play a role in development.

Three transcript variants encoding two distinct isoforms have been identified for this gene.

A pseudogene for this locus is located on chromosome 6.