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Mouse Microtubule-Associated Protein 1 Light Chain 3 beta,MAP1LC3B ELI
Price
3,140.00 ₪
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes).
Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.
Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
{ECO:0000250|UniProtKB:Q9GZQ8}.
Quantity
Storage and Stability
2-8ºC
Sensitivity
2.55ng/L
Detection range
5-1500ng/L
Shipping Conditions
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