Mouse Myc Proto-oncogene Protein, MYC ELI

Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'.

Activates the transcription of growth-related genes.

Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis.

Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells.

Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (PubMed: 31005419).