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Mouse Neurogenic locus notch homolog protein 3,NOTCH3 ELI
Price
3,140.00 ₪
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination.
Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus.
Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity).
May play a role during CNS development.
{ECO:0000250|UniProtKB:Q9R172, ECO:0000250|UniProtKB:Q9UM47}.
Quantity
Storage and Stability
2-8ºC
Sensitivity
0.09ng/ml
Detection range
0.19-12ng/ml
Shipping Conditions
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