Mouse Nuclear Pore Glycoprotein P62, NUP62 ELI

Essential component of the nuclear pore complex.

The N-terminal is probably involved in nucleocytoplasmic transport.

The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex.

Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation.

It might be involved in protein recruitment to the centrosome after nuclear breakdown.