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Mouse paired box 6,PAX6 ELI
Price
3,140.00 ₪
Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas.
Required for the differentiation of pancreatic islet alpha cells (PubMed:9163426).
Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters.
Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity).
Acts as a transcriptional repressor of NFATC1-mediated gene expression (PubMed:23990468).
{ECO:0000250, ECO:0000269|PubMed:23990468, ECO:0000269|PubMed:9163426}.
Quantity
Storage and Stability
2-8ºC
Sensitivity
9.72ng/L
Detection range
20-6000ng/L
Shipping Conditions
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