Mouse Secretoglobin Family 3A Member 2, SCGB3A2 ELI

Secreted cytokine-like protein (By similarity).

Binds to the scavenger receptor MARCO (By similarity).

Can also bind to pathogens including the Gram-positive bacterium L.monocytogenes, the Gram-negative bacterium P.aeruginosa, and yeast (By similarity).

Strongly inhibits phospholipase A2 (PLA2G1B) activity (PubMed: 24213919).

Seems to have anti-inflammatory effects in respiratory epithelium (PubMed: 16456148, PubMed: 25242865).

Also has anti-fibrotic activity in lung (PubMed: 24213919, PubMed: 26559674).

May play a role in fetal lung development and maturation (PubMed: 18535256).

Promotes branching morphogenesis during early stages of lung development (PubMed: 18535256).

In the pituitary, may inhibit production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) (PubMed: 24514953).