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Mouse Steroid 21-hydroxylase,CYP21B ELI
Price
3,140.00 ₪
A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis.
Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-deoxycortisol, intermediate metabolites in the biosynthetic pathway of mineralocorticoids and glucocorticoids.
Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
{ECO:0000250|UniProtKB:P00191, ECO:0000250|UniProtKB:P08686}.
Quantity
Storage and Stability
2-8ºC
Sensitivity
0.62ng/ml
Detection range
1.25-80ng/ml
Shipping Conditions
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