Porcine cytochrome P450 2E1,CYP2E1 ELI

A cytochrome P450 monooxygenase involved in the metabolism of fatty acids.

Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase).

Catalyzes the hydroxylation of carbon-hydrogen bonds.

Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids.

May be involved in the oxidative metabolism of xenobiotics.

{ECO:0000250|UniProtKB:P05181}.