Rabbit DNA repair protein RAD51 homolog 1,RAD51 ELI
3,140.00 ₪
Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR).
Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity.
Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template.
Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange.
Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR.
Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.
Also involved in interstrand cross-link repair.
{ECO:0000250|UniProtKB:Q06609}.
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