Rabbit Heat Shock Protein 90kDa Beta 1,HSP90b1 ELI

Molecular chaperone that functions in the processing and transport of secreted proteins.

When associated with CNPY3, required for proper folding of Toll-like receptors.

Functions in endoplasmic reticulum associated degradation (ERAD).

Has ATPase activity.

May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10 (By similarity).

{ECO:0000250|UniProtKB:P08113, ECO:0000250|UniProtKB:P14625}.