Rat 5-Hydroxytryptamine Receptor 6,HTR6 ELI

This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen.

The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

It has a high affinity for tricyclic psychotropic drugs (PubMed:7680751).

Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity (By similarity).

Is an activator of TOR signaling (By similarity).

{ECO:0000250|UniProtKB:P50406, ECO:0000250|UniProtKB:Q9R1C8, ECO:0000269|PubMed:7680751}.