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Rat Alpha-ketoglutarate dehy-drogenase,OGDH ELI

Price

3,140.00 ₪

2-oxoglutarate dehydrogenase (E1) component of the 2-oxoglutarate dehydrogenase complex (OGDHC), which mediates the decarboxylation of alpha-ketoglutarate (PubMed:18783430).

The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) (Probable).

The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion.

A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A.

{ECO:0000250|UniProtKB:Q02218, ECO:0000305|PubMed:18783430}.

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

9.93ng/L

Detection range

20-4500ng/L

Shipping Conditions

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