Rat Angiopoietin-like Protein 2, ANGPTL2 ELI

Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites.

Required for proper architecture of actin filaments.

Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus.

Participates in angiogenesis.

May play a role in the polarity, proliferation and migration of endothelial cells.

Selectively promotes FGF-induced MAPK activation through SRC (By similarity).