Rat Cold-inducible RNA-binding Protein, CIRBP ELI

Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival.

Acts as a translational activator.

Seems to play an essential role in cold-induced suppression of cell proliferation.

Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN.

Acts as a translational repressor.

Promotes assembly of stress granules (SGs), when overexpressed (By similarity).