Rat Excitatory amino acid transporter 2,SLC1A2 ELI

Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:1448170, PubMed:7913472).

Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (PubMed:1448170).

Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (By similarity).

Essential for the rapid removal of released glutamate from the synaptic cleft, and for terminating the postsynaptic action of glutamate (By similarity).

{ECO:0000250|UniProtKB:P43004, ECO:0000250|UniProtKB:P43006, ECO:0000269|PubMed:1448170, ECO:0000269|PubMed:7913472}.