Rat High mobility group protein A1,HMGA1 ELI

HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA.

It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts.

They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions (By similarity).

{ECO:0000250}.