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Rat Interleukin-23 Subunit Alpha, IL23A ELI
Price
3,140.00 ₪
Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity.
IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues.
IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines.
IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis (By similarity).
Quantity
Storage and Stability
2-8ºC
Sensitivity
0.27ng/L
Detection range
0.5-200ng/L
Shipping Conditions
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