Rat Lactadherin, MFGE8 ELI

Contributes to phagocytic removal of apoptotic cells in many tissues.

Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing.

Promotes VEGF-dependent neovascularization (By similarity).

Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors.

Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner.

Zona pellucida-binding protein which may play a role in gamete interaction.

Appears to participate in the O-acetylation of GD3 ganglioside sialic acid.