Rat Microtubule-associated Proteins 1A, 1B Light Chain 3B, MAP1LC3B ELI

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes).

Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.

Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.

Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.