Rat Oncostatin-M, OSM ELI

Growth regulator.

Inhibits the proliferation of a number of tumor cell lines.

It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells (By similarity).

Uses only type II OSM receptor (heterodimers composed of OSMR and IL6ST).

Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.