Rat P-Selectin, SELP ELI

Ca2+-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes.

Mediates the interaction of activated endothelial cells or platelets with leukocytes.

The ligand recognized is sialyl-Lewis X.

Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG.