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Rat protein phosphatase 1 regulatory subunit 15A,PPP1R15A ELI
Price
3,140.00 ₪
Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress.
Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1.
May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.
{ECO:0000269|PubMed:15674324}.
Quantity
Storage and Stability
2-8ºC
Sensitivity
7.23ng/L
Detection range
15-3000ng/L
Shipping Conditions
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