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Rat Protein Tyrosine Phosphatase Non Receptor Type 11,PTPN11 ELI

Price

‏3,140.00 ‏₪

Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus (By similarity).

Positively regulates MAPK signal transduction pathway.

Dephosphorylates GAB1, ARHGAP35 and EGFR.

Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulation of its RhoA binding activity.

Dephosphorylates CDC73 (By similarity).

Dephosphorylates SOX9 on tyrosine residues, leading to inactivate SOX9 and promote ossification (By similarity).

{ECO:0000250|UniProtKB:P35235, ECO:0000250|UniProtKB:Q06124}.

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

12.21ng/L

Detection range

30-9000ng/L

Shipping Conditions

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