Rat S100 calcium binding protein B,S100B ELI

Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer.

Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites.

Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase.

Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.

Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization.

May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

{ECO:0000269|PubMed:19910580, ECO:0000269|PubMed:20351179}.