Rat Scavenger Receptor Class B Member 1, SCARB1 ELI

Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells.

Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux.

Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL.

May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity.