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Rat Smoothened,SMO ELI

Price

3,140.00 ₪

G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal.

Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO).

Required for the accumulation of KIF7, GLI2 and GLI3 in the cilia.

Interacts with DLG5 at the ciliary base to induce the accumulation of KIF7 and GLI2 at the ciliary tip for GLI2 activation.

{ECO:0000250|UniProtKB:P56726, ECO:0000250|UniProtKB:Q99835}.

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

9.19ng/L

Detection range

20-3500ng/L

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