Rat Sodium/Glucose Cotransporter 1, SGLT1 ELI

Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1.

Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.