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Rat Squalene synthase,FDFT1 ELI
Price
3,140.00 ₪
Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene (PubMed:9575210).
Proceeds in two distinct steps.
In the first half-reaction, two molecules of FPP react to form the stable presqualene diphosphate intermediate (PSQPP), with concomitant release of a proton and a molecule of inorganic diphosphate.
In the second half-reaction, PSQPP undergoes heterolysis, isomerization, and reduction with NADPH or NADH to form squalene.
It is the first committed enzyme of the sterol biosynthesis pathway (By similarity).
{ECO:0000250|UniProtKB:P37268, ECO:0000269|PubMed:9575210}.
Quantity
Storage and Stability
2-8ºC
Sensitivity
0.11ng/ml
Detection range
0.25-16ng/ml
Shipping Conditions
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