Rat Tyrosine-protein Phosphatase Non-receptor Type 6, PTPN6 ELI

Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR.

The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates.

Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation.

Plays a key role in hematopoiesis.