Rat Zinc Transporter 3, SLC30A3 ELI

Zinc transporter 3 also known as solute carrier family 30 member 3 is a protein in humans that is encoded by the SLC30A3 gene.

The SLC30A3 gene codes for the ZnT-3 SLC30A family membrane transport protein.

ZnT-3 is required for the accumulation of zinc ions inside synaptic vesicles.

In mice, ZnT-3 is required for some forms of memory that depend on the hippocampus and the amygdala.

Zinc transport by ZnT-3 modulates memory formation by acting through the extracellular signal-regulated kinases signaling pathway.

Angiotensin II-induced senescence of vascular smooth muscle cells requires down-regulation of ZnT-3 and ZnT-10.